KEGG   REACTION: R04862
Entry
R04862                      Reaction                               
Name
(1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)
Definition
Homoisocitrate + NAD+ <=> Oxaloglutarate + NADH + H+
Equation
C05662 + C00003 <=> C05533 + C00004 + C00080
Comment
first step of R01934 (R04862 + R01936)
subsequently R01936
Reaction class
RC00001  C00003_C00004
RC00084  C05533_C05662
Enzyme
1.1.1.87        1.1.1.286
Pathway
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.87
     R04862  Homoisocitrate + NAD+ <=> Oxaloglutarate + NADH + H+
    1.1.1.286
     R04862  Homoisocitrate + NAD+ <=> Oxaloglutarate + NADH + H+
Orthology
K05824  homoisocitrate dehydrogenase [EC:1.1.1.87]
K10978  methanogen homoisocitrate dehydrogenase [EC:1.1.1.87 1.1.1.-]
K17753  isocitrate--homoisocitrate dehydrogenase [EC:1.1.1.286]

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG RCLASS (2)   
Gene (375)   
   KEGG ORTHOLOGY (3)   
   KEGG GENES (372)   
All databases (387)   

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